Vfold Pipeline offers a new user-friendly approach to the fully automated prediction of RNA 3D structures with given sequences. It first predicts 2D structures using the Vfold2D model [1-6] and then predicts 3D structures based on the predicted 2D structures using the Vfold3D [7] and VfoldLA [8] models. The Vfold3D/VfoldLA methods are based on the assembly of A-form helices with loop and/or motif templates, extracted from the known RNA 3D structures.
Due to the limitation of the current template library, Vfold Pipeline may give no predictions.